2020 Updates: RSR interviews an antibodies CEO and regularly updates this survey of the field

The mainstream media should be running weekly headlines
updating the public on the latest progress with targeted antibody treatment.
For some reason though, for now, if you want to keep up with the latest astounding
cancer treatment developments, you'll have to keep tuning in to BEL and Real Science Radio!

* How Can This Help a Cancer Patient? (Updated: 3/20/20) Medicine's still in the early years of cancer immunotherapy treatment. So don't assume that your oncologist will know or, knowing, even recommend such. Rather, you can ask your doctor if he knows whether targeted antibody (immunotherapy) treatment and open trials are available for your particular cancer. (And, if you're wealthy, for various reasons, request a full genome sequence of your cancer!) First though, you may want to listen to today's program and carefully read this article!

* Lung Cancer Too: Incredible results should not give false hope to all sufferers, but cautious hope to many. A British media report on a late-stage lung cancer "cure" using antibody treatment (immunotherapy) virtually cured a bedridden hospice patient with advanced lung cancer that has metastasized to his lymph nodes. His oncologist gave this 50-year-old two weeks to live (though such estimates can be notoriously wrong). But two weeks after his antibody treatment with the drug called Opdivo, a drug already available in the U.S., he recovered and returned home, even though previously, his lung cancer already had spread to his vocal cords and lymph nodes. Check out also, "...'remarkable' success fighting end-stage lung cancer in trials, experts say. It is also effective against other cancers" and listen to this report here on BEL.

* Jan 2020 Update: Three papers published together in the journal Nature have added to our targeted antibody arsenal new powerful weapons called B-cells and the in-tumor factories that make them. RSR hopes that with so many major breakthroughs, by 2022, immunotherapy will move to the top of the treatment ladder.

* Feb 2019 Update: Here are two from among the BEL listeners who've had a positive experience asking their oncologists about targeted antibodies. First, Brad H. from Vancouver, BC (kgov.com/brad-2015) called off-air on 2/14/19. His father, who's bladder was removed as its cancer spead to his lymph nodes, had two rounds of chemo with no apparent benefit. Brad thanks BEL for suggesting that patients urge their oncologist to explore immunotherapy. For now, a year after being accepted into a trial, Brad's father appears to be cancer free! Then, RSR listener Tom Healey, 83, passed away after asking for and then receiving an immunotherapy treatment that, while it didn't overcome his deteriorated heath, did enable his own marrow to again produce red blood cells!

* April 2019 Update: More than 1 in 4 go into full remission in small lymphoma immunotherapy trial, now going into larger clinical trial including for breast and head-and-neck cancers. (And see below; this article has been updated throughout 2019!)

* June 2018 Update: Florida woman cured of advanced breast cancer. See the BBC's report on the U.S. National Cancer Institute's amazing success with Judy Perkins, given three months to live and now recovered and still thriving [as of 2019] three years after her cure from the most common form of breast cancer!

* Oct 2018 Update: Two cancer immunotherapy researchers win the 2018 Nobel Prize in Medicine!

* Targeted Antibodies Cancer Treatment Revolution: Among the stunning results for targeted antibodies cancer treatment, CBS News reported on 35 terminally-ill advanced-stage leukemia sufferers. The disease went into remission in 94%, or 33 of 35 patients. Dr. Michael Grossbard, New York University's Perlmutter Cancer Center leukemia specialist told CBS News, "Oncologists are reluctant to use the word extraordinary. But these [results] are extraordinary. These are really remarkable findings..."

* FDA Approval: The FDA has approved Novartis' Kymriah to treat children with acute leukemia. Because various methods of cancer immunotherapy exist, the media and even the FDA itself will claim one or another of these early immunotherapy drugs (see below for those already approved in the U.S.) as a "first". Methods include checkpoint inhibitors and the actual modification of antibodies. See below for more. But first, there's this, right up the street from RSR's studio...

* ArcherDX in Boulder, Colorado: ArcherDX spearheaded the effort to extend the life of 12-year old Zaida. Real Science Radio host Bob Enyart interviews ArcherDX CEO Jason Myers to discuss Zaida's case and to get a better understanding both of this revolution in cancer treatment and of how targeted immunotherapy works. Studies in the U.S. and the U.K. are seeing hundreds of patients with many types of cancer virtually "cured", as some oncologists are now putting it. Not every patient though responds well, and some few have even died from the treatment. Update: Sadly, Zaida herself passed away on March 10, 2017 and while RSR would like to learn the specific cause, of course the family's privacy desires comes first. Overall though, the widespread success is stunning. ArcherDX provides the technology so that a patient's doctor can find out quickly what specific mutations may be causing the cancer. Now, a growing number of oncologists will be offering their patients the greatest of hope through individualized treatment that, like an archer aiming at a target, just might hit the bullseye. Online at ArcherDX.com, this next-generation sequencing (NGS) firm develops what is called target enrichment chemistry.

* Cancers Already Being Successfully Treated: People suffer from more than 100 major types of cancer. And while antibody treatment has resulted in some relatively rare autoimmune or other negative and even lethal side effects, the more common positive treatment experiences range in degree, from significantly extending life expectancy, stopping further tumor growth, and actually shrinking tumors, to major remission, and even to apparent cure. The types of cancer already being successfully treated with immunotherapy, using either the inhibitor or the re-targeting approach, include:
- Lung cancer (non-small cell with 30-50% response rates as of Feb. 2017)
- Childhood leukemia / leukemia
- Hodgkin lymphoma
- Non-Hodgkin lymphoma
- Lymph node cancer
- Melanoma skin cancer (Updates: 2018; 2019)
- Forms of breast cancer (including some success with TNBC)
- Kidney (renal cell) carcinoma (Update: 12/2019) 
- Bladder (urothelial) cancer
- Head cancers
- Neck cancers
(Please don't hesitate to email updates to this list to Bob@rsr.org.)

* Targeted Antibodies Trials, Success Stories, News, and RSR Broadcasts: The public awareness of the current revolution in cancer antibody treatment should explode in the 2020s. As with all medicines, patients respond with great variability. However, the following results and ongoing trials are greatly encouraging:
- 2019: Progression-free breast cancer survival improves in a Phase III trial for more than a quarter of the women using antibody drug Margetuximab.
- 2019: Non-small cell lung cancer (NSCLC), the most common type of lung cancer, now in first-ever human trials for a vaccine-type treatment.
- 2019: Late-stage prostate cancer patients in recombinant virus vaccine trial.
- 2019: AI software discovers patterns in lung cancer CT scans that indicate whether a patient is likely or not to benefit from immunotherapy (which is still expensive enough to deplete within a year the life savings of nearly half of patients on it).  

* UPDATE: Ah, finally, here at KGOV, now we're the ones guilty of fake news! See a video of a fire consuming a 

* CREV Headlines on RSR: Bob Enyart welcomes back to Real Science Radio the former JPL employee David Coppedge to once again discuss amazing scientific discoveries. Coppedge is a former NASA Cassini Saturn mission lead ground systems administrator and author of the Creation-Evolution Headlines site over at crev.info. One might think that by now, secular scientists would have figured out how the Moon go there, it being the closest of all celestial bodies. Yet, while they want people to believe that they can explain how the universe got here, the galaxies, the stars, and the planets, in reality, they can't even explain how the Moon got here. The guys also discuss how the latest discoveries about Pluto and Ceres once again fundamentally contradict the secular worldview. And the guys discuss yet another mammal that ate dinosaurs, biomimetics, and the grotesque inhumanity inspired by Darwinism.

EVENTS -- RIDDLE: 7 p.m. Thurs., Feb. 2nd hear creationist Mike Riddle in Arvada, Colorado at Peace Lutheran Church and again there from 8:30 a.m. to 5:30 p.m. on Sat., Feb. 4th attend Mike's "Beginning Creation Training" seminar!

EVENT -- ENYART: At 9 a.m. tomorrow, Saturday, January 28, come out to hear Bob Enyart as the keynote speaker at Colorado RTL's 2017 March for Life across the street from Denver's Planned Parenthood. UPDATE: See Bob's talk on the BEL YouTube channel or see it right here:

* RSR Interviews Illustra Media's Science Film Producer: Real Science Radio host Bob Enyart welcomes back Lad Allen of Illustra Media to discuss his latest film, ORIGIN: Design, Chance and the First Life on Earth. Featuring scientists Paul Nelson and Ann Gauger (and narration by Alvin Chea of Take Six), ORIGIN presents spectacular computer animation and cutting-edge research to examine the question that has baffled science: How did life on Earth begin? Today, most researchers insist it arose through simple chemistry that—without direction or plan—transformed inanimate matter into the first living cell. Yet, this explanation is devoid of evidence and unsatisfying, even to many of its most ardent supporters. As ORIGIN exposes the flaws of materialistic theories, you’ll travel through a molecular universe to encounter extraordinary biological engineering fundamental to the survival of every organism that has ever existed, engineering that points clearly to intelligence and mind. RSR recommends: Buy ORIGIN now, at Amazon.com on DVD or Blu-ray!

* Protein Sequence Analog from Physics: Discussing the 2018 Nobel Prize in physics, University of Nottingham's Prof. Mike Merrifield said, "Unfortunately, of all the many ways of sticking things together, 99.999% of them are complete rubbish." And with proteins, add a bunch more nines, and you get the idea.

*  One Dead Protein: Bob Enyart points out that even if a trillion universes all pulled together to overcome the odds of a protein forming and folding by chance, with that natural processes producing a first protein... so what? All you'd have is a single, non-living protein molecule. (By the way, Bob ran this by Dr. James Tour at rsr.org/tour.)

* Anti-Darwinist from Cambridge-based Protein Center on RSR: Hear Dr. Doug Axe at rsr.org/axe describe how Darwinism retarded science (as its often done) terribly slowing down the world's leading scientists from recognizing that the functional proteins have minimal tolerance and are very dependent upon the order of the amino acids that constitute them.

* #AloneTogether: For our coronavirus quarantine Lad Allen and Illustra Media have uploaded the full Origin film so we can all freely watch it at home. Thank you Lad!

* See BEL's Own Evolution Simulation Software: We've paid out $2,000 so far to people running our simulator at rsr.org/evolve! Too fun!

* 2020 Update: Published Oxford University research on their hoped for "extraterrestrial life" finds evolutionary events likely "extraordinarily improbable, even in conducive environments" and "expected evolutionary transition times likely exceed the lifetime of Earth, perhaps by many orders of magnitude." So, "Our results corroborate the original argument suggested by Brandon Carter that intelligent life in the Universe is exceptionally rare" and "provides a number of testable predictions, such as... that planets orbiting M dwarf stars are uninhabitable." Popular Mechanics summed it up, "Intelligent Life Really Can't Exist Anywhere Else."

* AloneTogether Coronavirus DBC Sermon: Updated 3/29/20, here's Pastor Bob's sermon using animation from Origin...

* For the First Monday that Donald Trump Woke Up in the White House: (post-show update) See the full-page Washington Times ad run by Colorado Right To Life to urge the Congress, the Supreme Court, and the new Trump administration, to learn what is right and to do what is right, by the most innocent among us.

IF THERE IS NO GOD
President Trump...

* Why Is There A Crack that Circles the Earth? Today's Real Science Radio program is the seventh in our continuing series, RSR's List of Answers to Hydroplate Theory Objections. Mechanical engineer Bryan Nickel talks with Bob Enyart about Michael Oard's objection to the global manner in which Walt Brown’s flood model presents the failure of the Earth's crust. Mr. Oard's critique of Dr. Brown's theory appears on creation.com, the (fabulous) website run by CMI, Creation Ministries International. If pressure in a subterranean chamber (the great deep) built up, Michael questions why the crust would "burst in a linear fashion" as explained by the HPT, and "not through one or several openings... as one would expect." Nickel explains the answer to Michael's objection using super slow-motion YouTube videos, and based on the laws of physics, and as found in Walt's book, In the Beginning. Also, Bryan clarifies Oard's statement, making it clear that the HPT does not claim that the fountains burst forth "through the MOR [mid-oceanic ridge]" but that before the flood, there was no MOR! Rather, the globe-encircling mid-oceanic ridge is a scar left over from the fountains and roughly traces the crack.

* Super Slow Motion Video Illustrates Linear Failure: As explained by mechanical engineer Bryan Nickel, because of factors including
- elastic strain
- a form of potential energy known as strain energy
- kinetic energy
- stress concentration
materials commonly fail in a linear fashion, as illustrated by these super slow motion videos...

* Where did the Pacific's Continental Crust Go? For this sixth program in our continuing series, RSR's List of Answers to Hydroplate Theory Objections (see rsr.org/answers), Bob Enyart again interviews Kevin Lea, HPT expert and graduate of the U.S. Naval Nuclear Power Program, to discuss the "Missing Pacific Crust" objection to Dr. Walt Brown's Hydroplate Theory. In 2012 renowned geophysicist and creationist John Baumgardner objected to the HPT's "claim that a layer of buoyant granitic crust currently lies beneath the Pacific basin. ...continental crust is readily distinguished from mantle rock by modern seismic techniques." Dr. Baumgardner added that there was an "unmistakable absence of any thick layer of granitic crust in the Pacific basin." However, Lea and Enyart share the discoveries beneath the Pacific and Indian Oceans of many researchers, as published in the scientific literature, documenting the extensive "presence of continental-type crust in the oceans where oceanic crust might be expected [which] has been recognized from seismic information by a number of authors." (For more information, see rsr.org/albright and rsr.org/hpt.

* 2017 Show Update: More Sunken Continental Crust! Remember, all scientists work for Walt Brown. In this case, the Geological Society of America published in their peer-reviewed journal GSA Today that a 4.9 million square kilometer of "the southwest Pacific Ocean is made up of continental crust." 94% of that continental mass, dubbed Zealandia, is submerged. (See GSA's Flip PDF.)

As Walt Brown describes it, "Because the Pacific crust would not have dropped as 'one huge block' (as early geologists thought), its thousands of fragments, buried under and within the magma that rose to the surface, will be difficult to detect seismically. However, the largest block, greater in area than India, is now recognized as a 94% submerged continent called, Zealandia."

In Feb. 2020 the journal Geology reported Continental-scale geographic change across Zealandia during Paleogene subduction initiation. (Actually, that shouldn't say subduction, but subsidence. And the discovery of dinosaur blood proved scientifically that the geologic column does not represent millions of years but that a single recent global flood produced its sediments, strata, and fossils. So the million-year timeframes are invalid in the otherwise important Zealandia research.) About this, Christopher Carbone at Fox News reported in 'Lost continent' of Zealandia transformed by formation of the Pacific’s Ring of Fire:

The 'lost continent' of Zealandia, which is submerged beneath the Pacific Ocean, experienced a major upheaval...

...scientists now believe that the topographic transformation may have been related to a reactivation of ancient fault lines linked to the formation of the western Pacific's Ring of Fire.

Their timeframes are all wrong, so there were no "ancient" fractures to reactivate.

Scientists have long believed that Zealandia's crust began to thin...

Long? Remember, all scientists work for Walt Brown! And Zealandia was discovered and named only in 1995.

"These dramatic changes in northern Zealandia, an area about the size of India, coincided with buckling of rock layers (known as strata) and the formation of underwater volcanoes throughout the western Pacific," study co-authors Rupert Sutherland, a geophysicist at Te Herenga Waka-Victoria University of Wellington, and Gerald Dickens, of Rice University in Texas, wrote in The Conversation.

“One of the amazing things about our observations is that they reveal the early signs of the Ring of Fire were almost simultaneous throughout the western Pacific,” Sutherland said in a Geological Society of America press statement.

Sutherland and his colleagues have put forth a new mechanism: a so-called "subduction rupture event", which they compare to a massive, super-slow earthquake.

Actually, during the flood's continental drift phase (which is after its rupture and flood phases and before it's recovery phase) is when Zealandia began to sink. See the HPT's Sequence of Events at rsr.org/sequence.

“We don’t know where or why,” said Sutherland, “but something happened that locally induced movement, and when the fault started to slip, like in an earthquake the motion rapidly spread sideways onto adjacent parts of the fault system and then around the western Pacific.”

* Today's Resource: To order RSR's #1 best-selling video (although our big bang video is catching up!), just click...

The Global Flood and the Hydroplate Theory
Blu-ray, 2-DVD Set, Stream or HD Download!

* See RSR's COMPLETE Global Flood and Hydroplate Theory: New in 2018, we've made available online for free our full, best-selling flood video. (Also available on DVD & Blu-ray for sharing with friends. And to help underwrite making this more widely available, please consider a donation. Thanks so much!) We hope you enjoy this:

* Flood Video Menu Contents: Real Science Radio co-host Bob Enyart presents the scientific evidence for Dr. Walt Brown’s model of the global flood, along with the relevant biblical material. Enyart also discusses Brown's opponents and contrasts both the vapor canopy and catastrophic plate tectonics with the hydroplate theory.

DVD Vol. 1
1. Walt Brown, Creation Leaders, and Scripture
2. Hydroplate Theory & Scientific Evidence

DVD Vol. 2
3. Hydroplates vs. Plate Tectonics
Bonus: Origin of Earth's Radioactivity

The Blu-ray disc contains all parts on one disc.

* Get the Best Creation Science Book Ever Written: Just click on the cover of the book to purchase it from RSR (which also helps us to continue broadcasting)...

Does this Bob Enyart Live program qualify as a special edition of Real Science Radio? Perhaps someone in our BEL family of friends could give this a listen and then email Bob@KGOV.com to let us know if this show should be listed as an RSR program! (Also, if you'd like to, feel free to try your hand at writing a brief summary of the show.) Thanks! -The Crew at BEL

* Fifth Program in Our Continuing Series: For this fifth program in our continuing series, RSR's List of Answers to Hydroplate Theory Objections (see rsr.org/answers), Bob Enyart interviews Kevin Lea, formerly with the Puget Sound Naval Shipyard’s nuclear engineering department. Enyart and Lea discuss the "Geometry Problem", an out-dated but lingering criticism of Dr. Walt Brown's work. For estimating the pre-flood thickness of our planet's crust, decades ago Dr. Brown used the amount of material in the Earth's sedimentary layers to arrive at a starting estimate of 10 kilometers thick. Afterward, when evidence dictated that even more debris had been ejected by the fountains of the great deep, Brown increased the estimate to 10 miles. Finally, in the last few years, with far more "flood debris" located, the theory's estimate for the thickness of the crust as initially created now stands at 60 miles!

Geophysicist John Baumgardner's quarter-century-old criticism that a 10-mile thick crust cannot account for today's known thickness, a valid objection at the time, is no longer relevant. In 2012 Dr. Baumgardner wrote regarding the HPT's need "to increase crustal thickness of the continents by the factor of two... there is the geometry problem of not having enough crustal mass between the present continent and the adjacent ridge to achieve such a doubling of thickness..." Concluding today's Real Science Radio broadcast, Enyart and Lea discuss the evidence that required increasing the estimated thickness of the created crust! (For more information, see rsr.org/albright, rsr.org/hpt, and next week's conclusion to today's interview titled, "Kevin Lea Answers the 'Pacific Crust' Hydroplate Objection.")

From rsr.org/TNOs:

* TNO's Bunch Up. Here's Why: From Walt Brown's Origin of Asteroids, Meteoroids,and Trans-Neptunian Objects, a TNO authority, Christopher Crockett, points out:

All the objects beyond 150 astronomical units come closest to the sun, a point known as perihelion, at nearly the same time that they cross the plane of the solar system. There’s no reason for these perihelia to bunch up like that. Billions of years of evolution should have left the perihelia scattered, like the rest of the Kuiper Belt—unless something was holding the perihelia in place.

All 2,300 TNOs whose orbits are known (taken as a group) have ω (argument of perihelion) values that cluster near either 0° or 180°. Chance could produce such a departure from a random distribution only once out of 10,000 times!

See Analysis of trans-Neptunian objects and a proposed theory to explain their origin, 2017, MNRAS.

Anyone interested can duplicate these results provided by astronautics Professor R. B. Brown. He downloaded from the Jet Propulsion Laboratory’s Small-Body Database the orbital elements for all 2,300 TNOs with known orbits. He then constructed a histogram for w that showed two prominent peaks—one near ω=0° and one near ω=180°. A simple chi-square test showed that the distribution was non-uniform with a confidence level of 99.99%. Professor Brown concluded that “many TNOs recently received powerful thrusts from near the plane of the ecliptic. Thrusts directed up above the ecliptic, produced ω values near 0°; thrusts directed downward produced ω values near 180°. He projected many TNOs and asteroids back in time and showed that Neptune’s gravity could have provided that thrust for only a few of these bodies over the last 22,000 years. Therefore, other planets near the ecliptic plane were involved. Were these TNOs even closer to the Sun than Neptune?

If that thrust occurred millions of years ago, random perturbations would have smoothed out those peaks, so the values for w would have been spread out uniformly between 0° and 360°. Therefore, “recently” must be less than millions of years ago—perhaps 5,000 years ago.

* Updated January 2018 -- RSR's FULL GF & HPT video on YouTube: While our best-selling video is still available on DVD and Blu-ray (for yet another way to share with friends and to watch at home and to preserve it for the day when Google closes down our YouTube channel) in order to reach a few thousand additional folks, we've also made the FULL VIDEO now available on YouTube for free...

* Today's Resource: To order RSR's #1 best-selling video (although our big bang video is catching up!), just click...

The Global Flood and the Hydroplate Theory
Blu-ray, 2-DVD Set, Stream or HD Download!

Real Science Radio co-host Bob Enyart presents the scientific evidence for Dr. Walt Brown’s model of the global flood, along with the relevant biblical material. Enyart also discusses Brown's opponents and contrasts both the vapor canopy and catastrophic plate tectonics with the hydroplate theory.

DVD Vol. 1
1. Walt Brown, Creation Leaders, and Scripture
2. Hydroplate Theory & Scientific Evidence

DVD Vol. 2
3. Hydroplates vs. Plate Tectonics
Bonus: Origin of Earth's Radioactivity

The Blu-ray disc contains all parts on one disc. And for now, save $10 with our special introductory pricing which discounts the $50 retail price to $39.99!

* Get the Best Creation Science Book Ever Written: Just click on the cover of the book to purchase it from RSR (which also helps us to continue broadcasting)...

* Boulder, Colorado's Planetarium Show on Christ's Birth: Celebrating Christmas, Real Science Radio hopes you too enjoy this interview with the host of the University of Colorado's Fiske Planetarium presentation, The Astronomical Star of Bethlehem, amateur astronomer Gil Buller. From the planetarium's website, "This exciting program examines the sky at the time of the birth of Christ to see which astronomical phenomenon may have been the Star of Bethlehem." Bob Enyart recorded this interview in 2011.

* Orbital Mechanics Help Identify the Star of Bethlehem: Using computer-generated images of the night sky in ancient Israel, this planetarium program does in great style what Bob Enyart's DVD does using more modest computer simulation software. Click to get Bob's classic DVD, The Planets, Stars, and The Bible.

Today’s Resource: Get RSR's Big Bang video! Physicist Lawrence Krauss, NASA, etc., all say that it is the confirmed predictions of the big bang theory that have convinced them that the model is correct. So we invite you to Google: big bang predictions. You'll see that Google ranks our article, at rsr.org/bbp, #1 out of more than half-a-million relevant pages

* Available Now! The long-awaited astronomy video RSR's Evidence Against the Big Bang, is finally here! If you enjoy Real Science Radio and would like to help keep the guys broadcasting and reaching more people, you just might love getting your own copy of this really fun and informative video. This big bang video is persuasive in the way that RSR is known for and so it will also make a fabulous gift for yourself and for others, including creationists and non-creationists!

* In Quantities of 1, 4, and 10: Our full-length video has been described as a tour de force against the big bang theory! It's based on the top lines of evidence listed over at rsr.org/bb. Here are the formats and purchase options available:
- DVD or Blu-ray $34.99
- Download $29.99
- Christmas gift pricing 4 copies for $99.99
- Christmas pricing 10 copies for $199.99
This bulk pricing is available on our online store or by calling us at 1-800-8Enyart.

* Don't Capitulate: (You'll probably first want to hear Part 1 of this program!) Real Science Radio hosts Bob Enyart and Fred Williams conclude their discussion of the magazine editorial by Dr. Jonathan Sarfati about Christians who capitulate on creation. First though the guys report on Bob attending the Boulder banquet to celebrate the astounding recovery of a dying 12-year-old Colorado cancer patient who almost immediately rebounded after she received immunotherapy (aka targeted therapy). See this also at rsr.org/targeted-antibodies and as always, the guys highly recommend you subscribe, for yourself or a loved one or friend, to creation.com/magazine!